Poliomyelitis eradication requires surveillance for acute flaccid paralysis (AFP), and in all countries children with AFP who are younger than 15 years are investigated for poliovirus in stool. However, collection of two 8-g stool samples 24-h apart and within 14 days of onset of paralysis is not easy. Samples need to be stored below 8 C documented properly, and tested in an accredited laboratory.
Individuals without adequate stool samples are examined by a neurologist with electromyography and nerve-conduction and other tests. A national expert committee1 reviews these cases, decides whether any are poliomyelitis, and labels them as compatible poliomyelitis in accordance with WHO’s recommended virological classification scheme.[1,2] The occurrence of compatible poliomyelitis suggests a failure of the surveillance system.[3]
To avoid missing cases of paralytic poliomyelitis, the prevalence of non-poliomyelitis AFP should be at least 1 per 100 000 in children younger than age 15 years. To ensure that we identify the virus, 80% of AFP cases should have adequate stool samples. If these criteria are met and no cases of poliomyelitis are identified for 3 years consecutively, we can conclude fairly certainly that the country is free of poliovirus. However, if the frequency of adequate stool samples is 80%, then 80% of all poliomyelitis cases must be confirmed. India had certification-quality surveillance for the past 8 years. The prevalence of non-poliomyelitis AFP, which had been 2 per 100 000 since 1998, increased in 2004 to about 3 per 100 000 and approximately tripled in 2006 to 6•95 per 100 000.[2,4]